Masteron (Drostanolone Propionate)

Functions and Traits

Drostanolone Propionate is an anabolic androgenic steroid that first hit the market around 1970 under the trade name Masteron, manufactured by Syntex. However, the compound was actually developed by Syntex in 1959 along with Oxymetholone (Anadrol) but would not be released until well after Anadrol. Syntex would also provide the compound under numerous other brand names such as Masteril and Meteormon.

As a therapeutic agent, Masteron enjoyed two decades of success in combating advanced inoperable breast cancer in postmenopausal women. It would also become a popular cutting steroid among bodybuilders, which is where Masteron is currently most commonly found.

However, the original Masteron brand is no longer available; in fact, nearly every pharmaceutical brand on earth has been discontinued. This compound is still approved by the U.S. FDA, but it is rarely used in breast cancer treatment any longer in favor of other options.

The steroid is, however, still tremendously popular in competitive bodybuilding cycles and often considered essential to contest preparation.
As an anabolic, Masteron isn’t well ­known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass.

Benefits and Side Effects

Without question, the effects of Masteron will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean.

This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Masteron will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti­estrogenic effect will simply enhance this overall look.

Watch out for these side effects:

  • Hepatotoxicity: Masteron is not a hepatotoxic anabolic androgenic steroid and will present no stress or damage to the liver.
  • Androgenic: The side effects of Masteron can include those of an androgenic nature. Androgenic side effects can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Due to its androgenic nature, Masteron can produce virilization symptoms in women. Virilization symptoms can include body hair growth, a deepening of the vocal chords and clitoral enlargement.
  • Cardiovascular: Masteron can have a significant effect on cholesterol. This can result in an increase in LDL cholesterol, as well as a decrease in HDL cholesterol with the strongest emphasis on the latter. The total effect on cholesterol will not be as strong as often found in many oral steroids, specifically C17 Alpha alkylated steroids.
  • Estrogenic: Masteron does not aromatize and it does not carry any progestin nature making estrogenic side effects impossible with this steroid. This means gynecomastia and water retention will not be concerns. It also means high blood pressure that is sometimes caused by excess water retention will not be a concern.
  • Testosterone: Masteron will significantly suppress natural testosterone production making exogenous testosterone therapy important when using this steroid. Failure to include exogenous testosterone will lead most men to a low testosterone condition, which not only comes with numerous possible symptoms but is also extremely unhealthy.

Dosage and Administration

For female breast cancer treatment, standard dosing calls for 100mg three times per weeks for 8­-12 weeks. This will commonly lead to virilization symptoms that could be hard to reverse.

However, no one can deny it’s still better than cancer. For the female athlete, 50mg per week should be more than enough for a total of 4­6 weeks. Some women may find doses closer to 100mg per week to be justified if they tolerate the hormone well.

Doses of this range should be controllable for most women, but individual sensitivity must be kept in mind. Doses that go above the 100mg per week mark or beyond 4­6 weeks of use will more than likely produce virilization symptoms at some level.